Mapping microbes that influence women’s health

2025 Phoenix KEYS intern Matthew Hawkins (he/him) study a little-known bacterium to better understand its role in the uterus in the lab of Melissa Herbst-Kralovetz.

2025 Phoenix KEYS intern Matthew Hawkins (he/him) from Brophy College Preparatory worked with postdoctoral researcher Nicole Jimenez to improve women’s health through microbiome research. Photo by Deanna Rodriguez, BIO5 Institute

In the lab of Melissa Herbst-Kralovetz, professor of basic medical sciences and director of the Women’s Health Research Program at the University of Arizona College of Medicine – Phoenix, researchers focus on improving women’s health through microbiome research. Their goal is to understand how bacteria in the uterus may play a role in conditions like endometrial cancer, which affects the inner lining of the uterus and is one of the most common cancers in women. 

Phoenix KEYS intern Matthew Hawkins (he/him) worked with postdoctoral researcher Nicole Jimenez to study a little-known bacterium called Schaalia turicensis. This microbe has been linked to infections elsewhere in the body, but its role in the uterus is still a mystery. Hawkins helped grow the bacteria in the lab and compare its genetic code to similar strains.  

Two researchers in a lab examining petri dishes under a laminar flow hood.
Matthew Hawkins holding up streaked plates in the Melissa Herbst-Kralovetz lab. Photo by Deanna Rodriguez, BIO5 Institute

“Seeing his enthusiasm for science and the meaningful conversations he sparked, even with his own family, reminds me why I love mentoring,” said Jimenez. “This experience shows how early exposure to science can light a lifelong spark.” 

Herbst-Kralovetz agrees. “I was mentored as an undergrad, and it changed my entire career path. That’s why I want to pay it forward—supporting young scientists like Matthew is one of the most rewarding parts of what we do.” 

By studying its DNA, Hawkins hopes to help determine whether S. turicensis may influence the development of uterine disease. 

“I’m passionate about science because I want to help people, and I’ve learned just how big the gaps are in women’s health research,” said Hawkins. “My dream is to become a cardiothoracic surgeon, but no matter where I end up, I want to keep learning and collaborating to make a difference.” 

Three people, one in a lab coat and two in casual attire, smiling in a laboratory setting.
(Left to right) Melissa Herbst-Kralovetz, Matthew Hawkins, and Nicole Jimenez pose in their lab at the University of Arizona College of Medicine – Phoenix. Photo by Deanna Rodriguez, BIO5 Institute

Take a closer look at how KEYS interns are helping advance real-world research across Arizona.

By: Caroline Mosley Bartelme | September 2, 2025 | Original Post


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